Study overview
Studies from 2019 and 2023 examine calcium absorption and formulation properties through solubility experiments, cellular transport studies and animal models.
- Research focus
- Formulation research on compound calcium carbonate granules
- Study design
- Formulation and preclinical research perspective
- Study population
- In-vitro, cell and animal experiments
- Publication / contributor
- Current Medical Science; Journal of Food Biochemistry
Reading points
| Measure | Result | Context |
|---|---|---|
| Calcium absorption | Gastric acid suppression and exogenous weak acids | 2019 preclinical study |
| Formulation properties | In-vitro experiments, cellular transport and mouse models | 2023 study |
Interpretation
Complexation and inclusion concern formulation questions such as calcium release and absorption, and vitamin D3 stability. The 2019 paper examined solubility and absorption under different gastric-acid conditions; the 2023 paper also assessed stability, cellular transport and animal bone measures.
Together, the papers describe formulation properties at different experimental levels and help explain the relationship between technical design and observed behavior.
Study notes
This article discusses formulation and preclinical papers published in 2019 and 2023. References provide a publisher abstract and an abstract with bibliographic details, respectively.
In-vitro, cell and animal experiments provide complementary findings within their models. Human absorption and clinical outcomes are evaluated through human research.
References
Chen HD et al. Current Medical Science. 2019;39(2):337–342; Ma K et al. Journal of Food Biochemistry. 2023:5553926.
- Chen et al. Gastric acid conditions and calcium absorption (2019), publisher abstractArticle abstract
- Ma et al. Formulation and mouse osteoporosis research (2023), abstract and bibliographic recordBibliographic record with abstract
